Your Invisible, Essential Lymphatic System

lymphatic picWhat’s the mysterious other circulatory system we know little about? One question on a biology test was all we heard about the lymphatic system in our 20th century classrooms. But with 21st century discoveries, our body’s combined transportation, cleaning, and disease-fighting system should have its own chapter in every 21st century biology textbook.

Lympha was the Roman goddess of fresh water. The human lymphatic system transports fluid and waste from all parts of the body to central collecting organs - the thoracic duct, right lymphatic duct, and cisterna chyli. Like our veins, tiny lymphatic vessels have flaps that work like check valves in a hydraulic system to move fluid in one direction - toward these central organs – see illustrations.

The debris, pathogens, and products carried by Lympha’s waters (lymph) are filtered and analyzed in stations (called lymph nodes and lymphatic organs) throughout the body. lymphatic picThey are the first line of defense against pathogens, and often start an immune response to these microorganisms that make the body sick.

In the digestive system, lymphatic capillaries called lacteals in the small intestines collect fluids and long-chain fats to transport to the rest of the body. And in the brain, the glymphatic system uses lymphatic fluid to wash our brain cells while we sleep.

In 2010, scientists showed that the hair-sized lymphatic vessels drain and transport most fluid that exits the circulatory system into tissues. Previously, we thought veins did this important work – this was known as the Starling Principle. But the Revised Starling Principle includes the revolutionary new understanding that the lymphatic channels of our body’s sewer system are involved in all forms of fluid transport and inflamation drainage.

lymphatic picHumans build sewer systems to control water around our cities. Roads flood in heavy rain. Water shimmers as it races downhill to storm drains, which are connected by sewer pipes to central collecting and filtering ponds. When unblocked and undamaged, this system clears the streets in a few hours, and the water carries away dirt, leaves, and other debris. Like underground sewer pipes, lymphatic channels perform their essential work unseen and unappreciated…unless that ‘sewer pipe’ gets blocked or damaged.

Lymphatic Dysfunction can come from a genetic abnormality, disease, or injury. Human flooding, called swelling, edema, or inflammation, is typically cleared a short time after an accident or infection temporarily overwhelms the system. But blocked or slow lymphatic channels can lead to chronic, lifetime swelling called lymphedema. Millions of people have some stage of lymphedema, which can be treated by a Certified Lymphedema Therapist, usually a physical or occupational therapist with special training.

March 6 is World Lymphedema Day, designated to raise awareness about the mysterious, miraculous lymphatic system and research on lymphatic dysfunction. Celebrate by learning more about this invisible organ system, essential to our human ecosystem.

Want to Know More? Check out these resources:

Lymphatic system - Wikipedia

Anatomy of the Lymphatic and Immune Systems

LaMantia, Jean. Gut Lymphatics and Long Chain Triglycerides

Jessen NA, Munk AS, Lundgaard I, Nedergaard M. The Glymphatic System: A Beginner's Guide

J. Rodney Levick, C. Charles Michel, Microvascular fluid exchange and the revised Starling Principle

Hettrick H, Aviles F. All edema is lymphedema

Lymphatic Education and Research Network

Article written by Sharon S. Shepard (This email address is being protected from spambots. You need JavaScript enabled to view it.) and published in The Lighthouse Lymphedema Network Newsletter, February, 2024

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